Oxalyl chloride → HCID 20444701, compound

Participants

Reaction Steps

Oxalyl chloride (11.52 gms) in dry methylene dichloride (10 ml) was slowly added to a suspension of 5-(p-chlorophenyl)-2-methyl-3-pyridine carboxylic acid (10 g) in dry methylene dichloride (50 ml). After standing for 1 hour at room temperature, the mixture was concentrated and the residue washed with dry diethyl ether, collected and dried to give 5-(p-chlorophenyl)-2-methyl-3-chlorocarbonylpyridine hydrochloride (11.95 g).

Provenance & Evidence