Morpholine → HCID 178420830, compound

HRID 2418670Notes

Reaction equation

HRID 2418670 reaction equation
[OH:1][CH:2]([PH:4](=[O:6])[OH:5])[CH3:3].[NH:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1>CO>[OH:1][CH:2]([PH:4](=[O:5])[O-:6])[CH3:3].[NH2+:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1

Participants

4

Reactant 2

HCID 8083MorpholineHCID 178476830HCID 178476830, compound

Product 1

HCID 178420830HCID 178420830, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

To a solution of α-hydroxyethylphosphinic acid (330 mg) in methanol, a solution of morpholine (261 mg) in methanol (1 ml) was added, and the resultant mixture was stirred for 2 hours. After removal of methanol by distillation, there was obtained morpholinium α-hydroxyethylphosphinate (Compound No. 14) (556 mg). nD24.5 1.4621.

Workup

  1. customAfter removal of methanol
  2. distillationby distillation

Sources & evidence

ORD record
ord-050e83265e134dbeb4402e03e19cc7ed
Source dataset
uspto-grants-1984_09
Patent number
US04473561

Reaction notes

Loading…