Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 241869Generated: October 31, 2026

Hydrochloric Acid → HCID 58103573, compound

https://huagongshe.com/reaction/241869

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthanolHCID 702—
ReactantHCID 66872457HCID 66872457—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 58103573HCID 58103573—

Reaction Steps

(R)-N-((R)-Cyclopropyl(6-(trifluoromethyl)pyridin-3-yl)methyl)-2-methylpropane-2-sulfinamide (0.245 g, 0.765 mmol), ethanol (2.7 mL), and 4.0 M of hydrogen chloride in dioxane (2.7 mL) were combined and the mixture was stirred at rt overnight. Reaction was concentrated down to an oil and then redissolved and washed with ethanol 3 times, and concentrated. The residue was dried on the high vacuum overnight to obtain a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653091B2
Source datasetuspto-grants-2014_02
ORD IDord-6e7c17e630bf4a9aa98c86325b4d592f
Source noteuspto-grants-2014_02