Phosphorus oxychloride → HCID 11232044, compound

HRID 2418777Notes

Reaction equation

HRID 2418777 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][C:8]=2[S:16]([O-:19])(=O)=[O:17])[CH2:3][CH2:2]1.[Na+].P(Cl)(Cl)([Cl:23])=O>C(#N)C>[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][C:8]=2[S:16]([Cl:23])(=[O:19])=[O:17])[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 44654287HCID 44654287, compound

Product 1

HCID 11232044HCID 11232044, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

31 g (0.1 mol) of sodium 2-morpholino-5-nitrobenzenesulfonate obtained in Step (a) above and 60 ml (0.67 mol) of phosphorus oxychloride were added to 300 ml of acetonitrile and the mixture was refluxed by heating for 2 hours. After cooling, the reaction mixture was added to 600 ml of ice water. The crystals thus-precipitated were collected by filtration. Yield: 18.5 g (60%).

Workup

  1. temperaturethe mixture was refluxed
  2. temperatureby heating for 2 hours
  3. temperatureAfter cooling
  4. customThe crystals thus-precipitated
  5. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-cf063727e7894c9e9c726396a152be46
Source dataset
uspto-grants-1984_09
Patent number
US04473632

Reaction notes

Loading…