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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2418812Generated: October 26, 2026

Cyclohexanecarboxylic acid → 4-Cyclohexyl-6-fluoro-2-methylquinoline

https://huagongshe.com/reaction/2418812

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanecarboxylic acidHCID 7413—
Reactant6-Fluoro-2-methylquinolineHCID 70784—
ReagentCID 21864320HCID 21864320—
SolventDimethyl SulfoxideHCID 679—
SolventWaterHCID 962—
Product4-Cyclohexyl-6-fluoro-2-methylquinolineHCID 16328830662%

Reaction Conditions

Temperature40 °C

Provenance & Evidence

DOI10.1021/acs.orglett.8b02988
Source datasetMinisci dataset from Roche
ORD IDord-7e73da61f3af4edf974253293c9fc874
Source noteMinisci dataset from Roche