Cyclohexanecarboxylic acid → 4-Cyclohexyl-6-fluoro-2-methylquinoline

HRID 2418812Notes

Reaction equation

HRID 2418812 reaction equation
Cc1ccc2cc(F)ccc2n1.O=C(O)C1CCCCC1>CS(C)=O.N.O.O=S(=O)(O)OOS(=O)(=O)O>Cc1cc(C2CCCCC2)c2cc(F)ccc2n1

Participants

6

Reactant 2

HCID 7413Cyclohexanecarboxylic acidHCID 707846-Fluoro-2-methylquinoline

Product 1

HCID 1632883064-Cyclohexyl-6-fluoro-2-methylquinolineYield 62%

Reagents, catalysts & solvents 3

HCID 21864320CID 21864320ReagentHCID 679Dimethyl SulfoxideSolventHCID 962WaterSolvent

Conditions

Temperature
40 °C

Sources & evidence

ORD record
ord-7e73da61f3af4edf974253293c9fc874
Source dataset
Minisci dataset from Roche

Reaction notes

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