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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2418894Generated: October 26, 2026

2-Cyanopyrimidine → 5-Isopropylpyrimidine-2-carbonitrile

https://huagongshe.com/reaction/2418894

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-CyanopyrimidineHCID 2757979—
ReactantPropane-2-sulfinic acid;ZINCHCID 117778686—
Reagenttert-Butyl hydroperoxideHCID 6410—
SolventDimethyl SulfoxideHCID 679—
SolventWaterHCID 962—
Product5-Isopropylpyrimidine-2-carbonitrileHCID 6807721531%
Product4-Isopropylpyrimidine-2-carbonitrileHCID 11690078915%

Reaction Conditions

Temperature50 °C

Provenance & Evidence

DOI10.1038/nature11680
Source datasetMinisci dataset from Roche
ORD IDord-5a26c173c5de493690cc1c0af2653970
Source noteMinisci dataset from Roche