2-Methylquinoxaline → 2-Isopropyl-3-methylquinoxaline

HRID 2418900Notes

Reaction equation

HRID 2418900 reaction equation
CC(C)S(=O)O.Cc1cnc2ccccc2n1.[Zn]>CC(C)(C)OO.CS(C)=O.O>Cc1nc2ccccc2nc1C(C)C

Participants

6

Reactant 2

HCID 236862-MethylquinoxalineHCID 117778686Propane-2-sulfinic acid;ZINC

Product 1

HCID 126763402-Isopropyl-3-methylquinoxalineYield 43%

Reagents, catalysts & solvents 3

HCID 6410tert-Butyl hydroperoxideReagentHCID 679Dimethyl SulfoxideSolventHCID 962WaterSolvent

Conditions

Temperature
50 °C

Sources & evidence

ORD record
ord-21755b54d05841a9a2afe4f7dbf742e4
Source dataset
Minisci dataset from Roche

Reaction notes

Loading…