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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2418905Generated: October 25, 2026

Ethyl isonicotinate → Ethyl 2-(trifluoromethyl)pyridine-4-carboxylate

https://huagongshe.com/reaction/2418905

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl isonicotinateHCID 15291—
ReactantCID 89601280HCID 89601280—
Reagenttert-Butyl hydroperoxideHCID 6410—
SolventWaterHCID 962—
SolventDichloromethaneHCID 6344—
ProductEthyl 2-(trifluoromethyl)pyridine-4-carboxylateHCID 463114407%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/nature11680
Source datasetMinisci dataset from Roche
ORD IDord-d16d8f108c9f42eca8fbd6eaffe96107
Source noteMinisci dataset from Roche