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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2418911Generated: November 3, 2026

4-Pyridineacetic acid hydrochloride → 2-(Trifluoromethyl)-4-pyridineacetic acid

https://huagongshe.com/reaction/2418911

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Pyridineacetic acid hydrochlorideHCID 81097—
ReactantCID 89601280HCID 89601280—
Reagenttert-Butyl hydroperoxideHCID 6410—
SolventWaterHCID 962—
SolventDichloromethaneHCID 6344—
Product2-(Trifluoromethyl)-4-pyridineacetic acidHCID 7112336857%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/nature11680
Source datasetMinisci dataset from Roche
ORD IDord-316b8ce895954fe5a7b1712c65a9a0f2
Source noteMinisci dataset from Roche