Methanol → HCID 20315484, compound

HRID 2419323Notes

Reaction equation

[C:1]([NH:4][C:5]1[N:6]=[C:7](Br)[S:8][C:9]=1[CH3:10])(=[O:3])[CH3:2].[Na].[CH3:13][OH:14]>>[C:1]([NH:4][C:5]1[N:6]=[C:7]([O:14][CH3:13])[S:8][C:9]=1[CH3:10])(=[O:3])[CH3:2]

Participants

Reactant 3

HCID 887Methanol

HCID 5360545Sodium

HCID 20294040HCID 20294040, compound

Product 1

HCID 20315484HCID 20315484, compound

Procedure

4-Acetamido-2-bromo-5-methylthiazole (prepared by acylating 4-amino-2-bromo-5-methylthiazole with acetic anhydride) is treated with sodium in absolute methanol as described in Example 1 to give the title compound.

Sources & evidence

ORD record: ord-62e9a3fdc82e47a1bed129905b54966e
Source dataset: uspto-grants-1978_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04105773

Reaction notes

Loading…