HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acryloyl chloride → 4-Acrylamido-2-bromothiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acryloyl chloride | HCID 13140 | — |
| Reactant | 2-Bromo-1,3-thiazol-4-amine | HCID 20294042 | — |
| Product | 4-Acrylamido-2-bromothiazole | HCID 20377166 | — |
Reaction Steps
4-Amino-2-bromothiazole is treated with acryloylchloride to give 4-acrylamido-2-bromothiazole which is refluxed with sodium in absolute methanol for sufficient time to produce the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04105773 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-a22564a2ff784d88869e75707cbd69da |
| Source note | uspto-grants-1978_08 |