反应详情

Bromine (12g.) was added dropwise to a stirred solution of isopropyl 4-acetylphenoxyacetate (17.6g.) in benzene (200ml.) over 30 minutes. The solution was stirred for a further 15 minutes and then evaporated. The residue was crystallised from ether/hexane to give isopropyl 4-(bromoacetyl)phenoxyacetate, m.p. 60°-61° C.

1. customevaporated
2. customThe residue was crystallised from ether/hexane