HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formicin → 3-Acetamidomethylthio-2-methylpropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formicin | HCID 69365 | — |
| Reactant | 3-Mercaptoisobutyric acid | HCID 152910 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 3-Acetamidomethylthio-2-methylpropanoic acid | HCID 21319145 | — |
Reaction Steps
3-Mercapto-2-methylpropanoic acid (2.4 g.) and N-hydroxymethylacetamide (1.8 g.) are dissolved in trifluoroacetic acid and the solution is stored at room temperature for 1 hour. The trifluoroacetic acid is removed in vacuo and the residue is dried in vacuo over potassium hydroxide to yield 3-acetamidomethylthio-2-methylpropanoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04105776 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-9ce6ca10b0564db095d2593f683b4cff |
| Source note | uspto-grants-1978_08 |