反应详情

To a solution of 43.0 g. (1.0 mole) of ethyleneimine and 60.0 g. (0.5 mole) of styrene oxide is added 3 drops of water and 0.2 g. of potassium hydroxide. The mixture is heated at reflux for 11/2 hours. Distillation of the excess ethyleneimine from the crude product gives 55.6 g. (68%) of the crystalline product. Recrystallization gives pure dl-α-phenyl-1-aziridineethanol with melting point 74°-76° C.

1. temperatureThe mixture is heated
2. temperatureat reflux for 11/2 hours
3. distillationDistillation of the excess ethyleneimine from the crude product
4. customgives 55.6 g
5. customRecrystallization