HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2419551Generated: November 3, 2026
Phenyl Isothiocyanate → 5-Chloro-N-phenyl-1,3-benzodithiol-2-imine
https://huagongshe.com/reaction/2419551
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Phenyl Isothiocyanate | HCID 7673 | — |
| Reactant | 5-Chlorobenzo[d][1,2,3]thiadiazole | HCID 12494994 | — |
| Product | 5-Chloro-N-phenyl-1,3-benzodithiol-2-imine | HCID 20313848 | 24.6% |
Reaction Steps
Phenylisothiocyanate (8.8g) and 5-chloro-1,2,3-benzothiadiazole (3.75g) are combined under an inert atmosphere and heated at 220° C until nitrogen evolution ceases. Initial purification of the product is accomplished by dry column chromatography (600g alumina column, benzene solvent). The product is further purified with a methylene chloride wash and recrystallization (twice) from pentane to yield 1.5g of the title compound, melting point 71°-73° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04107175 |
|---|
| Source dataset | uspto-grants-1978_08 |
|---|
| ORD ID | ord-4a3ee462bb3d4e3585c441a3b603fcb3 |
|---|
| Source note | uspto-grants-1978_08 |
|---|
