HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Diisopropylamino)ethyl chloride → alpha-(p-Fluorophenyl)-alpha-[2-(diisopropylamino)ethyl]-alpha-[2-(dimethylamino)ethyl]acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Diisopropylamino)ethyl chloride | HCID 7312 | — |
| Reactant | 2-Chloro-N,N-dimethylethylamine | HCID 7901 | — |
| Reactant | 4-Diisopropylamino-2-phenyl-butyronitrile | HCID 12612210 | — |
| Reactant | alpha-(p-Fluorophenyl)-alpha-[2-(diisopropylamino)ethyl]acetonitrile | HCID 12612215 | — |
| Product | alpha-(p-Fluorophenyl)-alpha-[2-(diisopropylamino)ethyl]-alpha-[2-(dimethylamino)ethyl]acetonitrile | HCID 12612268 | — |
Reaction Steps
Substitution of equivalent quantities of α-(p-fluorophenyl)-α-[2-(diisopropylamino)ethyl]acetonitrile and 2-chloro-N,N-dimethylethylamine for α-[2-(diisopropylamino)ethyl]-α-phenylacetonitrile and 2-chloro-N,N-diisopropylethylamine called for respectively in the procedure of Example 2, Method B, there is obtained α-(p-fluorophenyl)-α-[2-(diisopropylamino)ethyl]-α-[2-(dimethylamino)ethyl]acetonitrile, as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04107205 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-f9eeb91683ef4b348af039198524a555 |
| Source note | uspto-grants-1978_08 |