Methanethiol → HCID 12493298, compound

HRID 2419655Notes

Reaction equation

HRID 2419655 reaction equation
C[S:2][C:3](=S)[NH:4][N:5]=[CH:6][C:7]1[N:8]=[CH:9][NH:10][CH:11]=1.CS>C1(OC2C=CC=CC=2)C=CC=CC=1>[CH:6]1[C:7]2[N:8]([CH:9]=[N:10][CH:11]=2)[C:3](=[S:2])[NH:4][N:5]=1

Participants

4

Reactant 2

HCID 878MethanethiolHCID 178504099HCID 178504099, compound

Product 1

HCID 12493298HCID 12493298, compound

Reagents, catalysts & solvents 1

HCID 7583Diphenyl EtherSolvent

Procedure

A suspension of 164.5 gm. of 3-(4-imidazolylmethylene)dithiocarbazic acid methyl ester in 1.2 liters of diphenyl ether is heated and stirred at 175° C. until the methylmercaptan evolution subsides (20 minutes). The precipitate obtained on cooling to room temperature is collected and washed with petroleum ether, then acetone. The precipitate is then slurried with 1.2 liters of boiling methanol and filtered while hot to give the desired product, m.p. 271°-273° C.

Workup

  1. additionA suspension of 164.5 gm
  2. customThe precipitate obtained
  3. customis collected
  4. washwashed with petroleum ether
  5. filtrationfiltered while hot

Sources & evidence

ORD record
ord-6932b84756c541a78c4f02562324a9f3
Source dataset
uspto-grants-1978_08
Patent number
US04107308

Reaction notes

Loading…