Methyl iodide → HCID 13548774, compound

Participants

Reaction Steps

To a solution of 0.23 gm. of sodium in 10 ml. of methanol is added 1.66 gm. of 6-methyl-imidazo[1,5-d]-as-triazine-4(3H)-thione with warming to produce a solution. The mixture is cooled to room temperature and 0.75 ml. of methyl iodide is added. Cooling overnight gives a solid which is recrystallized from a mixture of 20 ml. of acetone and 6 ml. of ethanol and treated with charcoal. This solid is recrystallized from 20 ml. of ethanol, giving the desired product, m.p. 182.5°-184° C.

Provenance & Evidence