Diphenyl Ether → HCID 13548681, compound

HRID 2419675Notes

Reaction equation

HRID 2419675 reaction equation
C([O:3][C:4](=O)[NH:5][N:6]=[CH:7][C:8]1[N:9]=[C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[NH:11][C:12]=1[CH3:13])C.C1(OC2C=CC=CC=2)C=CC=CC=1>>[CH3:13][C:12]1[N:11]=[C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:9]2[C:8]=1[CH:7]=[N:6][NH:5][C:4]2=[O:3]

Participants

3

Reactant 2

HCID 7583Diphenyl EtherHCID 136138544HCID 136138544, compound

Product 1

HCID 13548681HCID 13548681, compound

Procedure

An 8.33 gm. portion of 3-[(5-methyl-2-phenyl-4-imidazolyl)methylene]carbazic acid ethyl ester in 60 ml. of diphenyl ether is heated in an oil bath at 215°-230° C. for 20 minutes. The reaction mixture is diluted to 400 ml. with petroleum ether. The precipitate is collected and recrystallized from 350 ml. of benzene giving the desired product, m.p. 182°-184.5° C.

Workup

  1. additionThe reaction mixture is diluted to 400 ml
  2. customThe precipitate is collected
  3. customrecrystallized from 350 ml

Sources & evidence

ORD record
ord-888e48d8b4df4e19bc73dfd9b019c16c
Source dataset
uspto-grants-1978_08
Patent number
US04107308

Reaction notes

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