HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 1-Amino-2,3-dibenzylguanidine hydroiodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Pseudourea, 1,3-dibenzyl-2-methyl-2-thio-, hydriodide | HCID 203825 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Amino-2,3-dibenzylguanidine hydroiodide | HCID 20314398 | — |
Reaction Steps
A solution of 6 ml. of hydrazine hydrate and the solution of 1,3-dibenzyl-2-methylthiopseudourea hydroiodide from Example 13 in 500 ml. of absolute ethanol is heated at reflux for 4 hours and then evaporated to dryness under reduced pressure. The residual solid is crystallized from isopropyl alcohol twice giving the desired product as colorless crystals, m.p. 135°-137° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04107326 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-4133785f5443466580d6a13295424e4a |
| Source note | uspto-grants-1978_08 |