Hydrochloric Acid → HCID 178479723, compound

Participants

Reaction Steps

10 ml of N hydrochloric acid were added to a suspension of 3.2 g of the product of Step A in 250 ml of water and the mixture was heated to 40°-50° C and filtered to remove insolubles. The aqueous filtrate was concentrated to 30 ml and was vacuum filtered. The recovered precipitate was washed with water and dried to obtain the dihydrate of N-(1H-imidazol-2-yl)-4-hydroxy-8-trifluoromethyl-quinoline-3-carboxamide hydrochloride.

Provenance & Evidence