Phosphorus pentachloride → HCID 20314315, compound

HRID 2419813Notes

Reaction equation

HRID 2419813 reaction equation
[F:1][C:2]([F:16])([F:15])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][C:10](=O)[CH:11]([CH3:13])[CH3:12].P(Cl)(Cl)(Cl)(Cl)[Cl:18]>C1(C)C=CC=CC=1>[F:1][C:2]([F:16])([F:15])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]=[C:10]([Cl:18])[CH:11]([CH3:13])[CH3:12]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 669236HCID 669236, compound

Product 1

HCID 20314315HCID 20314315, compoundYield 99.3%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent2×

Procedure

A solution of 11.56 g of the product of Step A in 200 ml of toluene was added over 15 minutes to a suspension of 11.45 g of phosphorus pentachloride in 25 ml of toluene and after gas evolution ceased, the mixture was refluxed for 11/2 hours and was evaporated to dryness to obtain 12.4 g of N-(2-trifluoromethylphenyl)-2-methyl-propanimidoyl chloride as a yellow oil which was used as is for the next step.

Workup

  1. temperaturethe mixture was refluxed for 11/2 hours
  2. customwas evaporated to dryness

Sources & evidence

ORD record
ord-112f6aef2297486ab7fd44d8b5ed3fcc
Source dataset
uspto-grants-1978_08
Patent number
US04107310

Reaction notes

Loading…