HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiazole → HCID 178439956, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | HCID 178439958 | HCID 178439958 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178439956 | HCID 178439956 | 31.3% |
Reaction Steps
Using the procedure of Step F of Example 6, 6.3 g of the acid of Step E and 2.1 g of 2-amino-thiazole were reacted in the presence of dicyclohexylcarbodiimide in dimethylformamide to obtain 2.5 g of N-(2-thiazolyl)-4-hydroxy-2-n-propyl-8-trifluoromethyl-quinoline-3-carboxamide in the form of colorless crystals melting at 222° C after crystallization from acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04107310 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-a46b8d7e27a445b4a51127bd5a697e92 |
| Source note | uspto-grants-1978_08 |