Hydrogen Peroxide → HCID 20314614, compound

Participants

Reaction Steps

15 g (0.06 mol) of 4-(p-fluorophenylthio)-butyramidine hydrochloride dissolved in 50 ml of acetic acid are oxidised with 5.6 ml of hydrogen peroxide of 120 volumes strength in 1 hour at 50° C.The mixture is left to stand overnight and is then evaporated in vacuo and the residue is taken up in acetone, filtered off and recrystallised from isopropanol. CRL 40,267 is obtained in a yield of 76%; it is in the form of small white crystals. Melting point = 138° C.

Provenance & Evidence