Chloroacetamide → HCID 20312290, compound

HRID 2419978Notes

Reaction equation

HRID 2419978 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[CH:8][CH:7]=[C:6]2[CH3:13].[Cl:14][CH2:15][C:16]([NH2:18])=[O:17]>O1CCOCC1>[Cl-:14].[C:16]([CH2:15][N+:9]1[C:10]2[C:5](=[CH:4][C:3]([O:2][CH3:1])=[CH:12][CH:11]=2)[C:6]([CH3:13])=[CH:7][CH:8]=1)(=[O:17])[NH2:18]

Participants

4

Reactant 2

HCID 6580ChloroacetamideHCID 2587616-Methoxy-4-methylquinoline

Product 1

HCID 20312290HCID 20312290, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

In 30 ml of dioxane 17.3 g of 6-methoxylepidine (0.1 mole) and 11.3 g of chloroacetamide (0.12 mole) were refluxed for 8 hours and the precipitated crystals were collected, washed with acetone and dried. Yield, 24.18 g (8.78%); M.p., 240°-241° C.

Workup

  1. customthe precipitated crystals were collected
  2. washwashed with acetone
  3. customdried
  4. customYield
  5. customM.p., 240°-241° C.

Sources & evidence

ORD record
ord-c9c3fa2f529542bdb41009cad6365b6a
Source dataset
uspto-grants-1978_08
Patent number
US04108668

Reaction notes

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