2-isopropylidene-1-indanone → HCID 12220946, compound

HRID 2419981Notes

Reaction equation

HRID 2419981 reaction equation
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9][CH2:8][NH+:7]=1.[C:16](=[C:19]1[CH2:27][C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[C:20]1=O)([CH3:18])[CH3:17]>CO>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH3:18][C:16]1[C:19]2[CH2:27][C:26]3[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=3)[C:20]=2[N+:7]2[CH2:8][CH2:9][C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=3[C:6]=2[CH:17]=1

Participants

4

Reactant 2

HCID 15133342-isopropylidene-1-indanoneHCID 20312280HCID 20312280, compound

Product 1

HCID 12220946HCID 12220946, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3,4-Dihydroisoquinolinium perchlorate (2 g) and 2-isopropylidene-indan-1-one (2 g) were heated together at 150° for 2 hours. The reaction mixture was cooled and diluted with methanol. The product was collected by filtration and recrystallized from methanol.

Workup

  1. temperatureThe reaction mixture was cooled
  2. filtrationThe product was collected by filtration
  3. customrecrystallized from methanol

Sources & evidence

ORD record
ord-cc4c5aaa884f4b46b3e02b6dab696124
Source dataset
uspto-grants-1978_08
Patent number
US04108667

Reaction notes

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