HCID 12220937, compound → HCID 12220950, compound

HRID 2419983Notes

Reaction equation

HRID 2419983 reaction equation
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9][CH2:8][NH+:7]=1.[C:16](=[C:19]1[C:23](=O)[C:22]2[CH:25]=[CH:26][CH:27]=[CH:28][C:21]=2[S:20]1(=[O:30])=[O:29])([CH3:18])[CH3:17]>>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH3:18][C:16]1[C:19]2[S:20](=[O:30])(=[O:29])[C:21]3[CH:28]=[CH:27][CH:26]=[CH:25][C:22]=3[C:23]=2[N+:7]2[CH2:8][CH2:9][C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=3[C:6]=2[CH:17]=1

Participants

3

Reactant 2

HCID 12220937HCID 12220937, compoundHCID 20312280HCID 20312280, compound

Product 1

HCID 12220950HCID 12220950, compound

Procedure

3,4-Dihydroisoquinolinium perchlorate (1.2 g) and 2-isopropylidenebenzothien-3-one-1,1-dioxide (2 g) were heated together at 150° for 16 hours. The reaction mixture was triturated with hot methanol and filtered. The product was purified by recrystallization from acetonitrile. Yield 0.6 g, m.p. > 330°.

Workup

  1. customThe reaction mixture was triturated with hot methanol
  2. filtrationfiltered
  3. customThe product was purified by recrystallization from acetonitrile

Sources & evidence

ORD record
ord-cd9ffa57652b4da2a945d67a14fc0966
Source dataset
uspto-grants-1978_08
Patent number
US04108667

Reaction notes

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