2-(Propan-2-ylidene)cyclopentan-1-one → HCID 86735952, compound

HRID 2419984Notes

Reaction equation

HRID 2419984 reaction equation
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]=[CH:8][NH+:7]=1.[C:16](=[C:19]1[CH2:23][CH2:22][CH2:21][C:20]1=O)([CH3:18])[CH3:17]>CN(C)C=O.CO>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH3:18][C:16]1[C:19]2[C:23]([CH:22]=[CH:21][CH:20]=2)=[N+:7]2[C:6]([CH:17]=1)=[C:15]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]1=[CH:9][CH2:8]2

Participants

5

Reactant 2

HCID 53240552-(Propan-2-ylidene)cyclopentan-1-oneHCID 20312258HCID 20312258, compound

Product 1

HCID 86735952HCID 86735952, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

Isoquinolinium perchlorate (2.3 g) and 2-isopropylidene cyclopentanone (1.5 g) in dimethylformamide (5 ml) were refluxed for 18 hours. The reaction mixture was cooled, diluted with methanol and filtered. Purification was effected by recrystallization from acetonitrile (norite). Yield 1.5 g, m.p. > 300°,

Workup

  1. temperatureThe reaction mixture was cooled
  2. filtrationfiltered
  3. customPurification
  4. customwas effected by recrystallization from acetonitrile (norite)

Sources & evidence

ORD record
ord-296e019e3f3a4b60a1af9d11d185ad7a
Source dataset
uspto-grants-1978_08
Patent number
US04108667

Reaction notes

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