Hydrochloric Acid → Prothiocarb hydrochloride [ISO]

HRID 2420036Notes

Reaction equation

HRID 2420036 reaction equation
[CH2:1]([S:3][C:4](=[O:12])[NH:5][CH2:6][CH2:7][CH2:8][N:9]([CH3:11])[CH3:10])[CH3:2].[ClH:13]>CCOCC>[Cl-:13].[CH2:1]([S:3][C:4](=[O:12])[NH:5][CH2:6][CH2:7][CH2:8][NH+:9]([CH3:10])[CH3:11])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 29697Prothiocarb

Product 1

HCID 29696Prothiocarb hydrochloride [ISO]

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

14.25 g (0.075 mole) of N-(3-dimethylaminopropyl)-thiocarbamic acid-S-ethyl ester are dissolved in 250 ml of absolute ether. While stirring and cooling, dry HCl gas is introduced. After 1 hour the product is suction-filtered. One obtains 14.1 g (83.4% of the theory) of the Mp. 87°-93° C. After reprecipitation from isopropanol/ether one obtains a product of the Mp. 93°-94° C.

Workup

  1. temperaturecooling
  2. filtrationAfter 1 hour the product is suction-filtered
  3. customOne obtains 14.1 g (83.4% of the theory) of the Mp. 87°-93° C
  4. customAfter reprecipitation from isopropanol/ether one
  5. customobtains a product of the Mp. 93°-94° C.

Sources & evidence

ORD record
ord-ec01febba7ef4c04bc5991414eb69bb9
Source dataset
uspto-grants-1978_08
Patent number
US04108885

Reaction notes

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