1-Butanol → HCID 86735955, compound

Participants

Reaction Steps

21.0 g (0.1 mole) of N-(3-dimethylammoniopropyl)-carbamic acid ethyl ester chloride are suspended in 100 ml of n-butanol. Dry HCl gas is introduced into the suspension for a short time and the mixture is heated for 6 hours at 100° to 115° C while stirring, the hydrochloride going into solution and some ml of liquid distilling off. Then concentrate and drag the residue in vacuum. One obtains 18.0 g of nD20 = 1.4750.

Provenance & Evidence