Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 20313030 | HCID 20313030 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20313022 | HCID 20313022 | 84.4% |
Reaction Steps
One gram of ethyl 5-(4-methoxybenzyl)picolinate was dissolved in 20 ml. of ethyl alcohol saturated with hydrochloric acid. The solution was heated in a sealed tube at 120° C. for 24 hours. The solvent was distilled out and the residue was added with cold water. Crystals thus formed were collected by filtration and recrystallized from ethyl acetate to obtain 0.8 g of ethyl 5-(4-hydroxybenzyl)-picolinate as colorless needle-like crystals of a melting point of 153°~156° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04109000 |
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| Source dataset | uspto-grants-1978_08 |
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| ORD ID | ord-60dd8a19a58e4a8c855778cadaacfd9c |
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| Source note | uspto-grants-1978_08 |
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