Hydrochloric Acid → HCID 20311078, compound

HRID 2420202Notes

Reaction equation

HRID 2420202 reaction equation
[N+:1]([C:4]1[C:5]([O:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])=[CH:6][C:7]([NH:23]C(=O)C)=[C:8]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[CH:9]=1)([O-:3])=[O:2].Cl.[OH-].[Na+]>C(O)C>[N+:1]([C:4]1[C:5]([O:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])=[CH:6][C:7]([NH2:23])=[C:8]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[CH:9]=1)([O-:3])=[O:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 20311075HCID 20311075, compound

Product 1

HCID 20311078HCID 20311078, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4.6 g of the product of Stage 4 are boiled under reflux for a few hours with 1.5 ml of concentrated hydrochloric acid in ethanol until no more starting material can be detected. The mixture is then adjusted to neutral to alkaline with strong sodium hydroxide solution and precipitated with plenty of water. The deposit is filtered under suction, washed with water, stirred with acetonitrile, refiltered under suction and dried.

Workup

  1. customprecipitated with plenty of water
  2. filtrationThe deposit is filtered under suction
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-0fec58fb27744770b54fff10e3214132
Source dataset
uspto-grants-1978_08
Patent number
US04110113

Reaction notes

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