HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 1-Acetyl-6-methyldihydropyrimidine-2,4(1H,3H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Dihydro-6-methyl-2,4(1H,3H)-pyrimidinedione | HCID 97818 | — |
| Product | 1-Acetyl-6-methyldihydropyrimidine-2,4(1H,3H)-dione | HCID 54417015 | — |
Reaction Steps
In the manner described above, 65 gm (0.5 mol) of 6-methyl-5,6-dihydrouracil were reacted with 8 mols of acetic acid anhydride in the presence of 2 ml of H2SO4. The product recrystallized from isopropanol had a melting point of 107° C to 109° C and the following analysis values:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04110242 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-62d2ddad5bea4f4e83f5cef4a1dad2af |
| Source note | uspto-grants-1978_08 |