HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20311325, compound → HCID 20311326, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20311325 | HCID 20311325 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 20311326 | HCID 20311326 | — |
Reaction Steps
48 g (mol/5.36) of 2-methyl-(4'-chloro-2'-nitroanilino)-propionic acid, in 480 ml of tetrahydrofuran, are hydrogenated in the presence of 10 g of Raney nickel in a one-liter autoclave. H2 pressure when cold: 135 kg. Pressure drop (calculated 24.5 kg - actual 30 kg). Temperature: 70°-90° C. Duration: 21/2 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04110337 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-134846102b754ef6aeb65916e10fad4d |
| Source note | uspto-grants-1978_08 |