HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10515403, compound → HCID 20311330, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10515403 | HCID 10515403 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 20311330 | HCID 20311330 | — |
Reaction Steps
Using a one-liter autoclave, 53.4 g (0.206 mol) of 2-methyl-(5'-chloro-2'-nitroanilino)-propionic acid in solution in 500 ml of tetrahydrofuran are hydrogenated in the presence of 17 g of Raney nickel. Hydrogen pressure in the cold: 120 kg. Temperature 60° C. Duration: 1 hour. Pressure drop:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04110337 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-103544b0d8ae471b9a7ffe7a96f10c5b |
| Source note | uspto-grants-1978_08 |