Hydrochloric Acid → HCID 20311576, compound

HRID 2420367Notes

Reaction equation

HRID 2420367 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:12][C:11](=[O:13])[N:10]([CH3:14])[C:9]2=[NH:15])=[CH:4][CH:3]=1.Cl>>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[CH2:12][C:11](=[O:13])[N:10]([CH3:14])[C:9]2=[NH:15])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 38683Clazolimine

Product 1

HCID 20311576HCID 20311576, compound

Procedure

3.0 g. of 1-(p-chlorophenyl)-2-imino-3-methyl-4-oxoimidazolidine was dissolved in 25 ml. of ethanolic HCl. This solution was filtered and added to an excess of ether upon which the hydrochloride precipitated. This was filtered, dried, and recrystallized from ethanol to give 0.8 g. product, m.p. 276°-8° C. The ethanol filtrate was concentrated to give an additional 1.1 g. of material. The total yield of product was 1.9 g. (55%).

Workup

  1. filtrationThis solution was filtered
  2. additionadded to an excess of ether upon which the hydrochloride
  3. customprecipitated
  4. filtrationThis was filtered
  5. customdried
  6. customrecrystallized from ethanol
  7. customto give 0.8 g
  8. concentrationThe ethanol filtrate was concentrated
  9. customto give an additional 1.1 g

Sources & evidence

ORD record
ord-769f93e923bf4311a24a880900ca2546
Source dataset
uspto-grants-1978_08
Patent number
US04110445

Reaction notes

Loading…