Hydrazine → HCID 70595361, compound

Participants

Reaction Steps

A mixture of 3.23 g of 1-(4-oxopiperidino)-3-p-biphenylyl-butan-3-ol (obtainable from 1-chloro-3-p-biphenylyl-butan-3-ol and 4-piperidone), 1.5 g of KOH, 2.5 ml of 85% hydrazine and 25 ml of diethylene glycol is warmed at 100° for 1 hour. The temperature is raised slowly until the hydrazone is decomposed, and the mixture is boiled for a further 4 hours, cooled and worked up in the customary manner to give 1-piperidino-3-p-biphenylyl-butan-3-ol, m.p. 102° - 104°.

Provenance & Evidence