Phthalimide potassium salt → HCID 70595721, compound

HRID 2420607Notes

Reaction equation

HRID 2420607 reaction equation
Cl[CH2:2][CH2:3][C:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([OH:6])[CH3:5].[C:19]1(=[O:29])[NH:23][C:22](=[O:24])[C:21]2=[CH:25][CH:26]=[CH:27][CH:28]=[C:20]12.[K]>CN(C=O)C>[C:19]1(=[O:29])[N:23]([CH2:2][CH2:3][C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)([OH:6])[CH3:5])[C:22](=[O:24])[C:21]2=[CH:25][CH:26]=[CH:27][CH:28]=[C:20]12

Participants

4

Reactant 2

HCID 24194345Phthalimide potassium saltHCID 70595719HCID 70595719, compound

Product 1

HCID 70595721HCID 70595721, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 2.6 g of 1-chloro-3-p-biphenylyl-butan-3-ol, 2.04 g of potassium phthalimide and 40 ml of DMF is heated at 110° for 1.5 hours. After cooling, the mixture is worked up in the customary manner to give 1-phthalimido-3-p-biphenylyl-butan-3-ol, m.p. 153° - 155°.

Workup

  1. temperatureis heated at 110° for 1.5 hours
  2. temperatureAfter cooling

Sources & evidence

ORD record
ord-882605401a2d4c0782cca917cb7fb9e3
Source dataset
uspto-grants-1978_08
Patent number
US04110447

Reaction notes

Loading…