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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2420616Generated: November 1, 2026

1-Acetamido-3-(4'-fluoro-4-biphenylyl)-butane → 3-(4'-Fluoro-4-biphenylyl)butylamine

https://huagongshe.com/reaction/2420616

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Acetamido-3-(4'-fluoro-4-biphenylyl)-butaneHCID 20302705—
SolventPotassium HydroxideHCID 14797—
Product3-(4'-Fluoro-4-biphenylyl)butylamineHCID 20302108—

Reaction Steps

A solution of 28.5 g of 1-acetamido-3-(4'-fluoro-4-biphenylyl)-butane in 800 ml of 10% methanolic KOH solution is boiled for 48 hours. The solution is concentrated and worked up using water and ether to give 3-(4'-fluoro-4-biphenylyl)-butylamine; hydrochloride, m.p. 222° - 224°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04110447
Source datasetuspto-grants-1978_08
ORD IDord-a471968d826c439f961a6074a8a2cde7
Source noteuspto-grants-1978_08