HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 1-[1-(4-Chlorophenyl)cyclobutyl]-7-[3-(morpholin-4-ylsulfonyl)propoxy]-1,2,3,4-tetrahydroisoquinoline hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 3-({1-[1-(4-Chlorophenyl)cyclobutyl]-3,4-dihydroisoquinolin-7-yl}oxy)propane-1-sulfonyl chloride | HCID 58246196 | — |
| Product | 1-[1-(4-Chlorophenyl)cyclobutyl]-7-[3-(morpholin-4-ylsulfonyl)propoxy]-1,2,3,4-tetrahydroisoquinoline hydrochloride | HCID 44465552 | — |
Reaction Steps
The compound was prepared analogously to example 82 from 3-({1-[1-(4-chlorophenyl)cyclobutyl]-3,4-dihydroisoquinolin-7-yl}oxy)propane-1-sulfonyl chloride using morpholine in place of 1-propylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653100B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-9be73020f7d5450fbf894119868f6b91 |
| Source note | uspto-grants-2014_02 |