HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Oxo-4-(trifluoromethyl)-2,3-dihydro-1,3-thiazole-5-carboxylic acid → HCID 11409939, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Oxo-4-(trifluoromethyl)-2,3-dihydro-1,3-thiazole-5-carboxylic acid | HCID 19884576 | — |
| Reactant | HCID 59295995 | HCID 59295995 | — |
| Product | HCID 11409939 | HCID 11409939 | 35.7% |
Reaction Steps
Prepared as Example 1 using (2R)-1-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-3-(methylamino)propan-2-ol (150mg, 0.45 mmol) and 2-oxo-4-(trifluoromethyl)-2,3-dihydro-1,3-thiazole-5-carboxylic acid (0.096 g) to yield the title compound as a colourless solid (0.085 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956070B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-c40601e38a1842d78fbdcf75d499d1ec |
| Source note | uspto-grants-2011_06 |