HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 6-oxo-2-(pentafluoroethyl)-1,6-dihydropyridine-3-carboxylate → 6-Oxo-2-(pentafluoroethyl)-1,6-dihydropyridine-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 6-oxo-2-(pentafluoroethyl)-1,6-dihydropyridine-3-carboxylate | HCID 86611249 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 6-Oxo-2-(pentafluoroethyl)-1,6-dihydropyridine-3-carboxylic acid | HCID 86611250 | — |
Reaction Steps
A suspension of ethyl 6-oxo-2-(pentafluoroethyl)-1,6-dihydropyridine-3-carboxylate (0.300 g) in concentrated hydrochloric acid (10 mL) was heated at reflux for 20 h. The reaction mixture was cooled and a colourless solid filtered off (0.30 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956070B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-67aaf16c9a79433c8534522e96f7b38d |
| Source note | uspto-grants-2011_06 |