HRID2421043

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6386

tert-Butyl alcohol

C4H10O

反应SMILES：COC(=O)c1ccc(Cl)c(OCC(=O)OC(C)(C)C)c1

HCID67215087

未命名化合物

PRODUCTS

产物

反应SMILES：CC(C)(C)OC(=O)COc1cc(C(=O)O)ccc1Cl

HCID67214798

未命名化合物

收率 89.9%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID962

Water

H2O

PROCEDURE

实验过程

Methyl 3-(2-tert-butoxy-2-oxoethoxy)-4-chlorobenzoate (0.7 g) in 9:1 tert butanol:water was subjected to Antarctica B lipase for 6 d. Filtration and evaporation of the solvent yielded the subtitle compound as an off-white solid (0.6 g).

WORKUP

后处理

filtrationFiltration and evaporation of the solvent