HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butanol → 3-(2-Tert-butoxy-2-oxoethoxy)-4-chlorobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butanol | HCID 6386 | — |
| Reactant | Methyl 3-(2-tert-butoxy-2-oxoethoxy)-4-chlorobenzoate | HCID 67215087 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-(2-Tert-butoxy-2-oxoethoxy)-4-chlorobenzoic acid | HCID 67214798 | 89.9% |
Reaction Steps
Methyl 3-(2-tert-butoxy-2-oxoethoxy)-4-chlorobenzoate (0.7 g) in 9:1 tert butanol:water was subjected to Antarctica B lipase for 6 d. Filtration and evaporation of the solvent yielded the subtitle compound as an off-white solid (0.6 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956070B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-2a4a984cb75f44cda1ee1431d3326581 |
| Source note | uspto-grants-2011_06 |