HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 59025416, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | HCID 59025436 | HCID 59025436 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 59025416 | HCID 59025416 | — |
Reaction Steps
((1R,2S)-2-{[1-(tert-butoxycarbonyl)piperidin-4-yl]amino}cyclohexyl)acetic acid was dissolved in DMF (3 mL) and diisopropyl ethylamine (50 μL) and HATU (0.1 g, 0.26 mmol) was then added and the mixture stirred at room temperature over night. The solvent was then removed under reduced pressure and the mixture was diluted in dichloromethane. Washed with 1N NaOH and with brine and the solvent was then removed under reduced pressure to give the tile compound. MS (M+1): 323.24
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956069B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-04600ea21d23465e9f05df48d08ed566 |
| Source note | uspto-grants-2011_06 |