HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-3-phenyl-4-isoxazolecarbohydrazide → HCID 86613580, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-3-phenyl-4-isoxazolecarbohydrazide | HCID 727924 | — |
| Reactant | 2,6-Dichloronicotinic acid | HCID 854047 | — |
| Product | HCID 86613580 | HCID 86613580 | 35% |
Reaction Steps
As described for example 2, 5-methyl-3-phenyl-isoxazole-4-carboxylic acid hydrazide (400 mg, 1.84 mmol) was converted using 2,6-dichloronicotinic acid instead of o-toluic acid to the title compound (SiO2, heptane:ethyl acetate=80:20 to 40:60, 240 mg, 35%) which was obtained as a white solid. MS: m/e=373.0/375.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956074B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-285b436924bc4cb8b21a43dd35dbac62 |
| Source note | uspto-grants-2011_06 |