1-Methylpiperazine → 5-Bromo-2-(4-methylpiperazin-1-yl)pyridine

HRID 2421336Notes

Reaction equation

HRID 2421336 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=1.[CH3:9][N:10]1[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]1>>[Br:8][C:5]1[CH:6]=[CH:7][C:2]([N:13]2[CH2:14][CH2:15][N:10]([CH3:9])[CH2:11][CH2:12]2)=[N:3][CH:4]=1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 693532,5-Dibromopyridine

Product 1

HCID 164142065-Bromo-2-(4-methylpiperazin-1-yl)pyridine

Procedure

Prepared from 2,5-dibromopyridine and 4-methylpiperazine in a similar manner to Example 9(d).

Sources & evidence

ORD record
ord-f9aaebe26f9a4dec8daed7a46404bcea
Source dataset
uspto-grants-2011_06
Patent number
US07956084B2

Reaction notes

Loading…