Piperidine → 5-Bromo-2-(piperidin-1-yl)pyrimidine

HRID 2421339Notes

Reaction equation

HRID 2421339 reaction equation
Cl[C:2]1[N:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=1.[NH:9]1[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1>>[N:9]1([C:2]2[N:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=2)[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 6066655-Bromo-2-chloropyrimidine

Product 1

HCID 36146825-Bromo-2-(piperidin-1-yl)pyrimidine

Procedure

Prepared from 2-chloro-5-bromopyrimidine and piperidine by the method of Example 44 (b).

Sources & evidence

ORD record
ord-34e9706811ba4df2b99e278f618ad330
Source dataset
uspto-grants-2011_06
Patent number
US07956084B2

Reaction notes

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