2-Bromophenol → 1-Bromo-2-(cyclopropylmethoxy)benzene

HRID 2421379Notes

Reaction equation

[CH:1]1([CH2:4]Br)[CH2:3][CH2:2]1.[Br:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[OH:13].NC(NC1SC(C2C=CC=CC=2C=O)=CC=1C(N)=O)=O>>[Br:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[O:13][CH2:4][CH:1]1[CH2:2][CH2:3]1

Participants

Reactant 3

HCID 72442-Bromophenol

HCID 81503Bromomethylcyclopropane

HCID 21914464HCID 21914464, compound

Product 1

HCID 219143811-Bromo-2-(cyclopropylmethoxy)benzene

Conditions

Temperature: 75 °C

Procedure

Prepared from cyclopropylmethyl bromide and 2-bromophenol by the method of Example 42 (b) except that the reaction mixture was stirred at 75° C. for 4 h. This gave the product as a colourless oil.

Sources & evidence

ORD record: ord-d4cc4dc35c1a45eea80e8a166692e125
Source dataset: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07956084B2

Reaction notes

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